ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA
 SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU
 KOLIN-KLORID/UREA

Ivkić, Marijana

prikaz prve stranice dokumenta ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU KOLIN-KLORID/UREA

master's thesis

ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU KOLIN-KLORID/UREA

2018. urn:nbn:hr:181:838641

Ivkić, Marijana

Josip Juraj Strossmayer University of Osijek
Department of biology

Cite this document

APA 6th Edition

Ivkić, M. (2018). ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU KOLIN-KLORID/UREA (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:181:838641

MLA 8th Edition

Ivkić, Marijana. "ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU KOLIN-KLORID/UREA." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2018. https://urn.nsk.hr/urn:nbn:hr:181:838641

Chicago 17th Edition

Harvard

Ivkić, M. (2018). 'ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU KOLIN-KLORID/UREA', Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, accessed 25 December 2024, https://urn.nsk.hr/urn:nbn:hr:181:838641

Vancouver

Ivkić M. ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU KOLIN-KLORID/UREA [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology; 2018 [cited 2024 December 25] Available at: https://urn.nsk.hr/urn:nbn:hr:181:838641

IEEE

M. Ivkić, "ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU KOLIN-KLORID/UREA", Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, Osijek, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:181:838641

Cite this item: https://urn.nsk.hr/urn:nbn:hr:181:838641

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Title	ANTIBAKTERIJSKA I ANTIOKSIDATIVNA AKTIVNOST DERIVATA RODANINA SINTETIZIRANIH KNOEVENAGELOVOM KONDENZACIJOM U EUTEKTIČKOM OTAPALU KOLIN-KLORID/UREA
Title (english)	ANTIBACTERIAL AND ANTIOXIDATIVE ACTIVITY OF RHODANINE DERIVATES SYNTHESISED BY KNOEVENAGEL CONDENSATION IN DEEP EUTECTIC SOLVENT CHOLINE CHLORIDE/UREA
Author	Marijana Ivkić
Mentor	Valentina Pavić (mentor)
Mentor	Maja Molnar (komentor)
Committee member	Irena Labak (predsjednik povjerenstva)
Committee member	Valentina Pavić (član povjerenstva)
Committee member	Mirna Velki (član povjerenstva)
Granter	Josip Juraj Strossmayer University of Osijek Department of biology Osijek
Defense date and country	2018-11-16, Croatia
Scientific / art field, discipline and subdiscipline	NATURAL SCIENCES Biology
Abstract	Derivati rodanina su heterociklički organski spojevi koji pokazuju širok spektar bioloških aktivnosti. Uzrok tih aktivnosti su mnogostruke mogućnosti strukturalnih modifikacija kako rodanina tako i njegovih derivata. U svrhu optimizacije primjene derivata rodanina u farmaceutskoj industriji istražuju se i sintetski putovi koji udovoljavaju zahtjevima zelene kemije poput biorazgradivosti, ekonomičnosti i netoksičnosti. U ovom radu je sintetizirana serija derivata rodanina mehanizmom Knoevenagelove kondenzacije s različitim aromatskim aldehidima u zelenom, eutektičkom otapalu sastava kolin-klorid/urea. Sintetiziranim spojevima su ispitane in vitro ukupna antioksidativna aktivnost DPPH metodom te in vitro antibakterijska aktivnost metodom razrjeđivanja bujona uz određivanje minimalne inhibitorne koncentracije.
Abstract (english)	Rhodanine derivates are heterocyclic organic compounds which exhibit a wide range of biological activities. The reason behind that is a large number of structural modification possibilities of both rhodanine and its derivates. For the optimization of rhodanine derivates application in the pharmacological industry, synthetic pathways that adhere to the requitrments of green chemistry such as biodegradbility, economics and nontoxicity, are also being investigated. In this paper a series of rhodanine derivates were synthesised by the Knoevenagel condensation mechanism with various aromatic aldehydes in a green, deep eutectic solvent composed of choline chloride and urea. Total antioxidant activity, measured by DPPH method in vitro, and antibacterial activity, measured by broth dilution method with determination of minimum inhibitory concentracion in vitro, were also determined for synthesised compounds.
Keywords
Keywords (english)
Language	croatian
URN:NBN	urn:nbn:hr:181:838641
Study programme	Title: Master of Science Graduate University Study Programme in Biology and Chemistry; specializations in: Master Education In Chemistry and Biology Course: Master Education In Chemistry and Biology Study programme type: university Study level: graduate Academic / professional title: magistar/magistra edukacije biologije i kemije (magistar/magistra edukacije biologije i kemije)
Type of resource	Text
File origin	Born digital
Access conditions	Open access
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Created on	2018-11-29 10:03:38