prikaz prve stranice dokumenta Utjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora
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master's thesis
Utjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora
2023. urn:nbn:hr:181:250356
Fleis, Karlo
Josip Juraj Strossmayer University of Osijek
Department of biology

Cite this document

Fleis, K. (2023). Utjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:181:250356

Fleis, Karlo. "Utjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2023. https://urn.nsk.hr/urn:nbn:hr:181:250356

Fleis, Karlo. "Utjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2023. https://urn.nsk.hr/urn:nbn:hr:181:250356

Fleis, K. (2023). 'Utjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora', Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, accessed 15 April 2024, https://urn.nsk.hr/urn:nbn:hr:181:250356

Fleis K. Utjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology; 2023 [cited 2024 April 15] Available at: https://urn.nsk.hr/urn:nbn:hr:181:250356

K. Fleis, "Utjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora", Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, Osijek, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:181:250356

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Metadata
TitleUtjecaj hrane bogate mastima i šećerima na distribuciju gangliozida u maternici štakora
Title (english)Effect of high fat - high sugar diet on gangliosides distribution in rat uterus
AuthorKarlo Fleis
MentorSenka Blažetić (mentor)
Committee memberSenka Blažetić (predsjednik povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of biology
Osijek
Defense date and country2023-10-31, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Način prehrane može imati znatne posljedice na organizam pa tako i ekspresiju gangliozida. Izražajnosti gangliozida u miometriju pretilih ženki ukazije na značajnu ulogu gangliozida u patološkim mehanizmima koji su posljedica pretilosti. U pokusu su korištene ženke Sprague Dawley štakora stare 3 tjedna podijeljene u dvije skupine. Kontrolna skupina (12 ženki) hranjena je standardnom prehranom (SD), dok je testna skupina (12 ženki) hranjena masnom i slatkom hranom (HFHSD). Žrtvovanje životinja je izvršeno 21 dan trudnoće, tj. u terminu poroda. Odmah nakon žrtvovanja životinja, prikupljeni uzorci fiksirani i pohranjeni. Eksperimentom je dokazano da u miometriju ženki štakora hranjenih masnom i slatkom hranom dolazi do povećane izražajnosti GM1 i GD1a gangliozida. Prehrana bogata mastima i šećerima nije utjecala na izražajnost GT1b gangliozida u miometriju štakorica.
Abstract (english)
Diet can have significant consequences on the body and thus the expression of gangliosides The change in expression of gangliosides in the myometrium of obese rats indicates a significant role of gangliosides in the pathological mechanisms resulting from obesity. In the experiment, female Sprague Dawley rats aged 3 weeks were randomly divided into two groups. Until the end of the experiment, the control group was fed a standard diet (SD), while the test group was on a high fat high sugar diet (HFHSD). 6 weeks after the onset of the special diet, the females were mated, and the same diet continued until delivery. The animals were sacrificed on the 21st day of pregnancy, at the time of delivery. Immediately after animal sacrifice, the collected samples were fixed and stored. The experiment proved that there was an increased expression of GM1 and GD1a gangliosides in the myometrium of female rats fed high fat and high sugar diet. Diet rich in fats and sugars did not affect the expression of GT1b ganglioside in rat myometrium.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:181:250356
Study programmeTitle: Master of Science Graduate University Study Programme in Biology; specializations in: Master of Biology
Course: Master of Biology
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra biologije (magistar/magistra biologije)
Type of resourceText
File originBorn digital
Access conditionsClosed access
Terms of useLicence In copyright icon
Created on2023-11-13 10:21:10