prikaz prve stranice dokumenta Degu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti
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undergraduate thesis
Degu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti
2022. urn:nbn:hr:181:525993
Kiš, Ana
Josip Juraj Strossmayer University of Osijek
Department of biology

Cite this document

Kiš, A. (2022). Degu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:181:525993

Kiš, Ana. "Degu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2022. https://urn.nsk.hr/urn:nbn:hr:181:525993

Kiš, Ana. "Degu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2022. https://urn.nsk.hr/urn:nbn:hr:181:525993

Kiš, A. (2022). 'Degu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, accessed 12 November 2024, https://urn.nsk.hr/urn:nbn:hr:181:525993

Kiš A. Degu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology; 2022 [cited 2024 November 12] Available at: https://urn.nsk.hr/urn:nbn:hr:181:525993

A. Kiš, "Degu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, Osijek, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:181:525993

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Metadata
TitleDegu (Octodon degus Molina, 1782) kao model u istraživanju Alzheimerove bolesti
Title (english)Degu (Octodon degus Molina, 1782) as a model Alzheimers disease research
AuthorAna Kiš
MentorGoran Vignjević (mentor)
MentorAlma Mikuška (komentor)
Committee memberGoran Vignjević (predsjednik povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of biology
Osijek
Defense date and country2022-09-28, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Alzheimerova bolest je progresivna bolest mozga koja se prikazuje gubitkom pamćenja, promjenama osobnosti i sposobnosti rasuđivanja. Većina istraživanja ove bolesti provedena su na životinjama s kraćim životnim vijekom, zbog čega je teško istražiti simptome bolesti koji se javljaju u kasnijoj životnoj dobi. Degu (Octodon degus) je glodavac endem čileanskih Anda kod kojeg može spontano doći do kognitivnog pada povezanog s patologijom tau proteina i β-amiloida, te upalnim procesima u mozgu sličnih onima kod razvoja Alzheimerove bolesti. Bolesti poput dijabetesa tipa 2, ateroskleroze i retinalne degeneracije, često popratnih Alzheimerovoj bolesti, razvijaju se starenjem životinje, stoga je degu pogodan model za istraživanje bolesti povezanih sa starenjem u ljudi
Abstract (english)
Alzheimer’s disease is a progressive brain disease that is manifested by memory loss, personality changes, and reasoning abilities. Most research of this disease has been conducted in shorter lifespan animals, which makes it difficult to investigate the symptoms of the disease that occur at a later age. Degu (Octodon degus) is a rodent endemic to Chilean Andes that can spontaneously develop cognitive decline associated with tau protein and β- amyloid pathology, also inflammatory processes in the brain similar to those in the development of Alzheimer's disease. Diseases such as type 2 diabetes, atherosclerosis and retinal degeneration, often accompanying Alzheimer's disease, develop with the aging of the animal, so degu is a suitable model for researching agerelated diseases in humans.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:181:525993
Study programmeTitle: Undergraduate University Study Programme in Biology (Bachelor of Science)
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
Access conditionsClosed access
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Created on2022-11-02 10:52:06