prikaz prve stranice dokumenta EKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio)
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master's thesis
EKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio)
2018. urn:nbn:hr:181:152892
Matuha, Josipa
Josip Juraj Strossmayer University of Osijek
Department of biology

Cite this document

Matuha, J. (2018). EKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio) (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:181:152892

Matuha, Josipa. "EKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio)." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2018. https://urn.nsk.hr/urn:nbn:hr:181:152892

Matuha, Josipa. "EKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio)." Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2018. https://urn.nsk.hr/urn:nbn:hr:181:152892

Matuha, J. (2018). 'EKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio)', Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, accessed 14 November 2024, https://urn.nsk.hr/urn:nbn:hr:181:152892

Matuha J. EKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio) [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology; 2018 [cited 2024 November 14] Available at: https://urn.nsk.hr/urn:nbn:hr:181:152892

J. Matuha, "EKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio)", Master's thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, Osijek, 2018. Available at: https://urn.nsk.hr/urn:nbn:hr:181:152892

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Metadata
TitleEKSPRESIJA LEPTINSKOG RECEPTORA U MOZGU ŠARANA (Cyprinus carpio)
Title (english)LEPTIN RECEPTOR EXPRESSION IN THE CARP (Cyprinus carpio) BRAIN
AuthorJosipa Matuha
MentorSenka Blažetić (mentor)
Committee memberIrena Labak (predsjednik povjerenstva)
Committee memberSenka Blažetić (član povjerenstva)
Committee memberValentina Pavić (član povjerenstva)
Committee memberRosemary Vuković (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of biology
Osijek
Defense date and country2018-07-13, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Prisutnost leptina uzrokuje smanjenje unosa hrane, dok se povišene razine kod pretilih osoba nazivaju leptinska rezistencija. Djelovanje leptina posredovano je leptinskim receptorom (OB–R). Najveća ekspresija receptora kod riba zabilježena je u jetri, dok je zanimljiv izostanak ekspresije u adipoznom tkivu. Kako je leptin jedna od glavnih signalnih molekula u mozgu glodavaca koja je ključna za kontrolu energetskog metabolizma pretpostavljeno je kako je ista ta moleukla glavni medijator kontrole unosa hrane kod riba. Lokalizacija leptinskog receptora u mozgu šarana provedena je na šaranima uzgojenim u polikulturama u ribnjacima PP Orahovica. Potvrda distribucije dvije izoforme leptinskog receptora (OB–R izoforma I i OB–R izoforma II) s različitom stopom ekspresije u različitim regijama mozga šarana pruža novi uvid u fiziologiju energetskog metabolizma riba.
Abstract (english)
The presence of leptin causes a decrease in food intake, while elevated levels in obese people are called leptin resistance. Leptin activity is mediated by leptin receptor (OB-R). The highest expression of the receptor in fish was observed in the liver, while the absence of expression in adipose tissue was interesting. Since leptin is one of the major signaling molecules in the rodent brain, which is crucial for controlling energy metabolism, it was assumed that the same was the main mediator of food intake control in the fish. The locus of leptin receptor in the brain carp was carried out on carp bred in polyculture in the ponds of PP Orahovica . Confirmation of the distribution of two isoforms of the leptin receptor (OB-R isoform I and OB-R isoform II) with different expression rates in different regions of the carpal brain provides a new insight into the physiology of energy metabolism of fish.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:181:152892
Study programmeTitle: Master of Science Graduate University Study Programme in Biology; specializations in: Master of Biology
Course: Master of Biology
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra biologije (magistar/magistra biologije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2018-07-20 06:52:02