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undergraduate thesis
Bakterijske spore
2017. urn:nbn:hr:181:892597
Ćosić, Josipa
Josip Juraj Strossmayer University of Osijek
Department of biology

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Ćosić, J. (2017). Bakterijske spore (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology. Retrieved from https://urn.nsk.hr/urn:nbn:hr:181:892597

Ćosić, Josipa. "Bakterijske spore." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2017. https://urn.nsk.hr/urn:nbn:hr:181:892597

Ćosić, Josipa. "Bakterijske spore." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, 2017. https://urn.nsk.hr/urn:nbn:hr:181:892597

Ćosić, J. (2017). 'Bakterijske spore', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, accessed 16 November 2024, https://urn.nsk.hr/urn:nbn:hr:181:892597

Ćosić J. Bakterijske spore [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, Department of biology; 2017 [cited 2024 November 16] Available at: https://urn.nsk.hr/urn:nbn:hr:181:892597

J. Ćosić, "Bakterijske spore", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, Department of biology, Osijek, 2017. Available at: https://urn.nsk.hr/urn:nbn:hr:181:892597

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Metadata
TitleBakterijske spore
Title (english)Bacterial endospores
AuthorJosipa Ćosić
MentorGoran Palijan (mentor)
Committee memberGoran Palijan (predsjednik povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
Department of biology
Osijek
Defense date and country2017-07-04, Croatia
Scientific / art field,
discipline and subdiscipline		NATURAL SCIENCES
Biology
Abstract
Bakterijske spore jedna su od prilagodbi bakterija na preživljavanje nepovoljnih uvjeta. U nedostatku nutrijenata bakterije formiraju dormantnu, metabolički inaktivnu i izuzetno otpornu stanicu koja čuva genetički materijal dok uvjeti ponovno ne postanu povoljni. Sporulirajuće vrste roda Clostridium su obligatni anaerobi te u proces germinacije i ponovnog nastanka vegetativne stanice ulaze samo u uvjetima nedostatka kisika. Upravo zbog toga svojstva smatraju se prikladnima za liječenja tumora koji sadržavaju hipoksične regije. Spore ovih vrsta unesene u organizam proklijale bi samo unutar hipoksičnih dijelova tumorskog tkiva te bi se mogle koristiti kao vektori za prijenos različitih protutumorskih lijekova.
Abstract (english)
Formation of spores is one of the adaptations of bacteria for surviving unfavourable conditions. When favored nutriens are exhausted, bacteria formes dormant – a metabolically inert and an extremely resistant cell - to preserve the cell´s genetic material in times of extreme stress. Sporulating species of Clostridium genus are obligate anaerobes and they selectively germinate in hipoxic conditions. This ability of clostridia spores makes them suitable for cancer therapies that target hypoxic regions of tumours. Injected spores of this species germinate only in hypoxic regions of tumour tissue and they could be used as delivery vehicles for different anti-cancer drugs.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:181:892597
Study programmeTitle: Undergraduate University Study Programme in Biology (Bachelor of Science)
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) biologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2017-09-28 11:00:15